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Delayed Pressure Urticaria is a rare type of chronic physical urticaria characterized by delayed onset of skin lesions at the sites of pressure applied to the skin. It is caused by an allergic reaction to pressure which results in hives, itching, and swelling at the affected area. It is believed that repeated pressure on an area of skin causes the release of inflammatory chemicals within the skin, leading to a delayed reaction. In some cases, Delayed Pressure Urticaria can cause life-threatening anaphylaxis. Treatment for Delayed Pressure Urticaria consists primarily of avoiding activities that trigger reactions and medications that reduce inflammation. Delayed Pressure Urticaria is a rare form of physical urticaria which causes hives, itching, and swelling after pressure is applied to the skin. It typically appears 10-60 minutes after pressure has been applied and can last for several hours. Symptoms usually occur on areas of the body that have been subjected to pressure, such as the arms, legs, or torso. In some cases, other areas of the body may also be affected

Delayed Pressure Urticaria

Delayed pressure urticaria (DPU) is a rare condition that causes hives to form in response to pressure applied to the skin. It is an allergic-type reaction to pressure, such as from clothing, jewelry, or even a hug. Symptoms can range from mild itching and redness to swelling and severe pain. The effects of DPU may last from several minutes up to several days and can be very uncomfortable.


The exact cause of DPU is unknown, but it is believed to be related to an abnormal immune response that triggers the release of histamine. Histamine is a type of chemical that helps the body respond to allergens or irritants. In people with DPU, histamine is released when pressure is applied to the skin, which causes inflammation and hives.

Risk Factors

DPU affects both men and women equally. It typically begins between the ages of 20-40 years old but can occur at any age. People with other forms of urticaria (also known as hives) are more likely to develop DPU than those with no history of allergies or hives. Additionally, people who have had certain types of infections or illnesses are also at higher risk for developing DPU.


The most common symptom of DPU is an itchy rash that appears in areas where pressure has been applied. This rash usually appears within minutes after the pressure has been applied and can last from a few minutes up to several days afterward. Other symptoms may include swelling, redness, warmth around the affected area, and pain or burning sensations in some cases. In severe cases, hives may spread throughout the body and cause difficulty breathing or other serious symptoms that require immediate medical attention.

Diagnosis and Treatment

Diagnosis of DPU is usually based on a person’s medical history and physical examination results combined with tests such as skin prick test or blood tests for allergens that could be causing reactions on contact with pressure on skin surface . Treatment options for DPU include avoiding triggers (such as tight-fitting clothing), taking antihistamines , topical corticosteroids , immunosuppressants , phototherapy , ultraviolet light therapy etc . In some cases laser treatment may also be recommended .

Common Causes of Delayed Pressure Urticaria

Delayed pressure urticaria (DPU) is a form of physical urticaria that occurs as a result of pressure being applied to the skin. It is an uncommon skin disorder that can cause severe itching, hives, and swelling at the affected sites. It can be difficult to diagnose and treat, as its symptoms can often be confused with other conditions. However, there are some common causes that may be responsible for this condition.

  • Infections: Infections caused by bacteria or viruses may trigger DPU. These infections often cause inflammation in the body, which can then lead to the formation of hives and other signs of DPU.
  • Medications: Certain medications such as antibiotics or anti-inflammatory drugs may also trigger DPU.
  • Allergens: Allergens such as pollen, dust mites, or animal dander can also lead to DPU in some people.
  • Environmental Factors: Exposure to extreme temperatures, sunlight, humidity, and other environmental factors may also trigger DPU in some cases.
  • Genetics: Genetics may also play a role in the development of DPU. People who have a family history of allergies or certain autoimmune diseases are more likely to develop this condition.

It is important to note that not everyone who experiences these conditions will develop DPU. However, if you are experiencing any of the above symptoms or have a family history of allergies or autoimmune diseases, it is important to speak with your doctor about your risks and possible treatments. Your doctor may recommend lifestyle changes such as avoiding certain triggers and/or medications that could make your condition worse. Additionally, they may prescribe medications such as antihistamines or corticosteroids to help reduce symptoms. With proper diagnosis and treatment, most people with DPU can manage their condition effectively.

Diagnosing Delayed Pressure Urticaria

Delayed Pressure Urticaria (DPU) is a type of physical urticaria, which is an allergic skin reaction caused by pressure or friction. It results in hives on the skin that can last up to 24 hours after the pressure has been applied. In order to diagnose DPU, a doctor will need to first examine the patient’s medical history and symptoms.

• Physical exam: The doctor will check for signs of hives or other skin reactions when pressure is applied to certain areas of the body. The doctor may also check for swelling and tenderness in the affected areas.

• Allergy testing: To confirm if an allergic reaction has occurred, the doctor may perform various allergy tests such as skin prick tests, patch tests, and blood tests.

• Imaging studies: If the doctor suspects that there may be an underlying condition causing the DPU, they may recommend imaging studies such as x-rays or MRI scans to rule out any other potential causes.

• Elimination diet: In some cases, an elimination diet may be recommended to determine if certain foods are triggering the allergic reaction. This involves avoiding certain foods for a period of time and then reintroducing them one at a time to see if any symptoms occur when eating them again.

Once all possible causes have been ruled out, a diagnosis can be made and treatment can begin. Treatment typically involves taking medications such as antihistamines or corticosteroids to reduce inflammation and itching. Other treatments such as topical creams or light therapy may also be recommended depending on the severity of the condition.

Treating Delayed Pressure Urticaria

Delayed pressure urticaria (DPU) is a rare type of chronic urticaria that develops from prolonged pressure on the skin. It has been recently recognized as a distinct clinical entity, although it has been reported in medical literature since at least 1930. Treatment of DPU can be challenging, and there are no universally accepted guidelines for managing this condition. However, there are some strategies that may be helpful in controlling symptoms and improving quality of life.

Avoidance of Triggers

The primary goal in treating DPU is to identify and avoid triggers that cause delayed hives. Common triggers include tight-fitting clothing, compression garments, tight belts or waistbands, backpacks, and even sitting or lying in one position for too long. Identifying these triggers and avoiding them whenever possible can help reduce the risk of developing hives.


Various medications have been used to treat DPU, including antihistamines, corticosteroids, leukotriene inhibitors, and mast cell stabilizers. It is important to discuss with your doctor which medications may be most effective for you. In some cases, combination therapy with multiple medications may be necessary to control symptoms.

Lifestyle Changes

In addition to avoiding triggers and taking medications as prescribed by your doctor, other lifestyle changes can also help manage DPU symptoms. These include maintaining a healthy weight through diet and exercise; wearing loose-fitting clothes; using pillows and cushions to avoid prolonged pressure on the skin; taking regular breaks from activities such as sitting or standing; and using heat or cold therapy when needed.

Complementary Therapies

Some people have found relief from their DPU symptoms through the use of complementary therapies such as acupuncture or yoga. While there is limited research on these treatments for DPU specifically, anecdotally they may provide some benefit in reducing hives or itching associated with the condition.

Overall, treating DPU can be a challenge but with patience and persistence it is possible to find relief from symptoms. Working closely with your doctor to identify individual triggers and develop an effective treatment plan can help improve quality of life for those living with this condition.

Managing Delayed Pressure Urticaria

Delayed Pressure Urticaria (DPU) is a skin condition that can cause raised, itchy welts on the skin. It typically occurs after pressure is applied to the skin and can be very uncomfortable. Unfortunately, there is no known cure for DPU, but there are ways you can manage your symptoms and reduce flares. Here are some tips for managing Delayed Pressure Urticaria:

  • Avoid triggers: Different people have different triggers, but some common triggers include tight clothing or jewelry, rubbing or pressure on the skin, and extreme temperatures.
  • Use anti-itch creams: Over-the-counter anti-itch creams such as hydrocortisone or calamine lotion can help sooth the itch associated with DPU.
  • Take antihistamines: Antihistamines like Benadryl can help reduce symptoms of itching and swelling associated with DPU. Be sure to talk to your doctor before taking any medication.
  • Stay cool: Heat can worsen DPU symptoms so try to stay cool when possible.
  • Wear loose clothing: Tight clothing can worsen symptoms so opt for loose fitting clothes when possible.
  • Avoid scratching: Scratching your skin can make symptoms worse and increase risk of infection.

These tips may help reduce the severity of your symptoms and make it easier for you to manage your condition. However, it’s important to talk to your doctor about any questions or concerns you may have about managing delayed pressure urticaria. Your doctor may also be able to recommend other treatments that may be more effective for you.

Complications of Delayed Pressure Urticaria

Delayed pressure urticaria (DPU) is a rare type of chronic hives caused by pressure applied to the skin. It can cause severe itching, burning, and swelling. Although the condition is not life-threatening, it can have serious complications if left untreated.

The most common complication of DPU is secondary skin infections. This occurs when bacteria or other infectious agents enter the skin through scratches or breaks caused by the constant itching and scratching associated with DPU. These infections can cause redness, swelling, and pain. They can also spread to other areas of the body if not treated promptly.

Another complication associated with DPU is anaphylaxis, which is a potentially life-threatening allergic reaction that causes swelling in the airways and difficulty breathing. Anaphylaxis typically occurs within minutes of exposure to an allergen or irritant and requires immediate medical attention. People with DPU are at an increased risk for anaphylaxis due to their hypersensitive skin reactions.

Patients with DPU may also experience psychological issues such as depression and anxiety due to the constant itching and discomfort associated with the condition. The social isolation that often accompanies chronic hives can also lead to depression and anxiety if not addressed in a timely manner.

Finally, people with DPU may be at risk for developing other conditions such as asthma or food allergies due to their hypersensitive reactions to certain stimuli. If you have DPU, it is important to talk to your doctor about any potential risks associated with your condition so that you can take steps to prevent further complications from developing.

Dealing with DPU can be challenging but there are steps you can take to manage your symptoms and reduce your risk of complications. Make sure you follow your doctor’s instructions for taking medications as prescribed and avoid triggers such as pressure on your skin or exposure to allergens or irritants whenever possible. You should also make sure you get plenty of rest and stay hydrated throughout the day in order to keep your symptoms under control. With proper management, people with DPU can live normal, healthy lives without fear of serious complications arising from their condition.

Prognosis for Delayed Pressure Urticaria

Delayed pressure urticaria is an allergic reaction to pressure or contact with certain materials. While the condition is not life-threatening, it can cause significant discomfort and distress. The prognosis for this condition can vary, depending on a variety of factors.

When it comes to the prognosis of delayed pressure urticaria, the most important factor is proper diagnosis and treatment. Treatment typically involves avoiding any substances or materials that trigger an allergic reaction and using medication to reduce symptoms. If these measures are taken, prognosis tends to be very good in most cases.

Another key factor in determining prognosis is how severe the reaction is. Mild reactions typically only last for a few hours after contact with a trigger substance, while more severe reactions can last up to several days or even weeks. In general, the more severe the reaction, the worse the prognosis will be.

The age of the person affected by delayed pressure urticaria is also important when it comes to prognosis. Children tend to have better outcomes than adults, likely due to their stronger immune systems and ability to recover from allergic reactions quickly.

Finally, the cause of delayed pressure urticaria plays an important role in determining prognosis. Allergic reactions caused by natural substances such as pollen or dust have a better outcome than those triggered by man-made substances such as latex or certain types of plastics.

Overall, delayed pressure urticaria has a good prognosis if proper treatment and avoidance measures are taken and if the severity of the reaction is mild enough that it does not last very long. Those affected should speak with a doctor about their specific situation in order to get a better idea of what they can expect from their condition in terms of prognosis and recovery time.

In Reflection on Delayed Pressure Urticaria

Delayed Pressure Urticaria (DPU) is a rare type of chronic urticaria that occurs in response to pressure applied to the skin. It is a condition that has been associated with a range of physical symptoms, including swelling, itching, and pain. While the exact cause of DPU remains unknown, recent research suggests that it may be linked to the release of inflammatory substances from mast cells in the skin. The condition can be difficult to diagnose and manage due to its unpredictable nature.

The most effective way to manage DPU is through lifestyle modifications and topical treatment options such as antihistamines and topical steroids. It is also important for people with DPU to identify potential triggers in order to avoid potential flare-ups. Additionally, cognitive behavioral therapy (CBT) may be helpful for patients struggling with anxiety or depression associated with DPU.

Although there is still much research needed on Delayed Pressure Urticaria, it is clear that it is a serious condition that should not be taken lightly. People suffering from this condition should seek medical advice and support from healthcare professionals in order to ensure an accurate diagnosis and effective treatment plan. By working together with their healthcare provider, those with DPU can take steps towards managing their symptoms and improving their quality of life.

, Delayed Pressure Urticaria is an unpredictable chronic urticaria condition that can cause significant physical discomfort and distress for those affected by it. It is important for people with DPU to seek medical advice in order to develop an effective treatment plan tailored specifically for them. With the right combination of lifestyle modifications, topical treatments, and psychological support, those affected by DPU may be able to manage their symptoms more effectively and improve their overall quality of life.

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