Scientific researches and findings have linked Xanthelasma and diabetes. Xanthelasma is majorly a collection of cholesterol around the eyelid, and it can lead to various health complications, including diabetes and ischemic heart diseases. No matter how much change is made to forestall cardiovascular risk factors, these conditions are still noticed in individuals suffering from Xanthelasma.
Keeping in mind the underlying causes of this condition, there is also a very strong link between Xanthelasma and diabetes, as well as atherosclerotic disease irrespective of a normal cholesterol level in the patient. Most patients think that the removal of Xanthelasma by a dermatologist is all that there is to it, but there is more to this condition than meets the eye. An experienced doctor would not just remove the fat accumulation around the eyes, but will also assess the patient for various underlying conditions, especially diabetes, and the various associated cardiovascular conditions.
What brought about the link between Xanthelasma and diabetes?
Xanthelasma, as described above, involves the accumulation of bad cholesterol around the eyelids and it is equally associated with fat deposits in various parts of the body including the walls of the blood vessel. Fat can serve as one of the sources for de novo synthesis of glucose; though, it is an energy-dependent process. The accumulation of fat means increased raw material is available for this de novo synthesis. Therefore, the glucose level will be raised via a process known as lipolysis, which is the breaking down of fat.
The increase in glucose synthesis translates to an increase in insulin synthesis at the early stage of the process; insulin has the function of converting excess glucose in the body to glucagon. So that the body can maintain a normal glucose level in blood circulation to meet the energy requirements of the body.Glucose serves as a source of ATP, which is the only form of energy recognized by the human body for its various metabolic processes.
However, the pancreases, the organ responsible for producing insulin, can get overworked over time if the excess glucose synthesis persists, and this will be the situation if the fat accumulation does not decrease. Once the pancreases are overworked, its ability to produce insulin from the islet of langerhans will reduce, and this will culminate to excess glucose in blood circulation; this excess glucose acts the foundation for the link between Xanthelasma and diabetes.
Medical science is improving by the day, and medical practitioners do not limit themselves anymore to merely assessing Xanthelasma when they notice it around the eyelid. Instead of this limited approach, the affected person is taken for further clinical and laboratory examination to find out if there are other underlying conditions that could have led to the Xanthelasma being noticed at the outside. In most cases, such underlying conditions are always present. Principal among the underlying conditions are the ones mentioned earlier, like atherosclerotic diseases, cardiovascular complications, and diabetes.
The condition is a blessing in disguise; the link between Xanthelasma and diabetes enables medical experts to easily detect the underlying condition on time before the diabetes aggravates, enabling them to effect the right treatments before it is too late.